In case you missed it, here’s a storify of a twitter conversation about starting a new lab. It’s full of wisdom for all freshly minted PIs. Some of my favorites are (slightly paraphrased):
You are the best postdoc you will have for many years – stay active at the bench for 2+ years
Your first paper as group leader will be like your first pancake – half baked and lumpy. Don’t wait for the perfect story to emerge – publish quickly to establish credibility and secure funding.
Go read the whole storify if you are starting now or will be starting soon.